What is AOD-9604?
AOD9604 is a fat burning peptide and a synthetic peptide fragment derived from human growth hormone (hGH) 177-191. It was developed to retain the fat-burning properties of hGH without its growth-promoting effects.
Research has explored AOD-9604’s role in:
✔️ Fat metabolism by stimulating lipolysis (fat breakdown)
✔️ Inhibiting lipogenesis (formation of new fat cells)
✔️ Obesity treatment models through targeted fat reduction
(Sources: Halford, 2006; Cheetham et al., 2001)
AOD-9604 and Fat Metabolism Research
Scientific Studies on AOD-9604 and Weight Loss
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A clinical trial published in Drug Discovery Today (2004) found that obese participants receiving 10 mg of AOD9604 daily for seven days showed increased fat metabolism with no adverse effects. (Cheetham et al., 2004)
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A study in Current Opinion in Investigational Drugs (2006) noted that AOD9604 could promote fat breakdown similar to natural hGH but without unwanted glucose metabolism effects. (Halford, 2006)
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An animal study on genetically obese rats demonstrated that AOD9604 treatment led to significant weight loss, highlighting its potential for reducing fat and boosting fat metabolism in these models. (Heffernan et al., 2001)
These findings suggest AOD-9604 may be effective for weight management research and obesity-related metabolic studies.
Mechanism of Action: How AOD-9604 Affects Body Fat
AOD9604 works by:
âś… Activating lipolysis, which breaks down stored fat to burn fat
âś… Preventing lipogenesis, stopping new fat cell formation
âś… Targeting adipose tissue, rather than affecting muscle or bone growth
AOD-9604 contains a synthetic lipolytic domain that facilitates fat metabolism, promoting fat-burning effects and aiding in weight loss.
These effects mimic the fat-reducing functions of hGH without increasing IGF-1 or affecting blood sugar regulation.
(Sources: Fawcett, 2004; Thevis & Schänzer, 2014)
Potential Research Benefits of AOD-9604
Research Area | Potential Findings |
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Obesity Treatment | May support fat loss by stimulating lipolysis. AOD-9604 can help reduce body weight by stimulating metabolism. |
Metabolic Disorders | May help regulate fat accumulation in metabolic research. Compared to natural growth hormone, AOD-9604 is considered safer and effective in stimulating metabolic processes without the associated side effects. |
Targeted Fat Reduction | May break down stubborn fat deposits. |
Clinical Safety | Studies suggest no impact on glucose metabolism. |
While promising, AOD-9604 is strictly for research use and not approved for human or veterinary applications.
Product Specifications for Research Use
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CAS Number: 221231-10-3
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Chemical Formula: C78H123N23O23S2
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Sequence: Tyr-Leu-Arg-Ile-Val-Glu-Gly-Ser-Ser-Arg-Leu-Phe-Asp-Arg-Lys
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Molar Mass: 1,819.1 g/mol
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Purity: Minimum 98%
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Storage: Keep refrigerated upon reconstitution.
Research Material Information:
✔️ Lyophilized sample in a sterile glass vial
✔️ 5 mg AOD9604 per vial
✔️ Diluent and laboratory supplies not included
For Research Use Only
This preparation is strictly for laboratory research purposes by qualified professionals. Research on AOD-9604 often includes a healthy diet to maximize the peptide’s effectiveness. AOD-9604 is not a drug, food, supplement, or cosmetic and should not be misbranded, misused, or mislabeled as such.
📌 Note: AOD9604 has not been evaluated by regulatory authorities and is not intended for human or veterinary use.
FAQs: AOD-9604 Research
AOD-9604 is studied for its role in fat metabolism, weight loss, and obesity models in research settings. It can support individuals on their weight loss journey by enhancing metabolism and fat loss.
Research suggests that AOD-9604 may help individuals lose weight by stimulating fat breakdown (lipolysis) while preventing fat storage (lipogenesis).
No. AOD-9604 is strictly for research purposes and has not been approved by the FDA for human or veterinary applications.
AOD-9604 is reconstituted and used in controlled laboratory experiments on fat metabolism and obesity models.
Conclusion
AOD-9604 peptide has been widely studied for its potential role in fat metabolism, obesity research, and weight management. Scientific research suggests that it may stimulate lipolysis, inhibit lipogenesis, and support fat loss without the negative effects of hGH. Additionally, AOD-9604 can be a valuable tool in the weight loss journey by promoting fat loss and metabolic health.
However, AOD-9604 is strictly for laboratory research purposes and has not been approved for human use. Ongoing studies continue to explore its full range of biological functions in fat metabolism research.
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Resources
1. Halford, J. C. (2006). Obesity drugs in clinical development. Current Opinion in Investigational Drugs, 7(4), 312.
2. Cheetham, S. C., Jackson, H. C., Vickers, S. P., Dickinson, K., Jones, R. B., & Heal, D. J. (2004). Novel targets for the treatment of obesity: a review of progress. Drug Discovery Today: Therapeutic Strategies, 1(2), 227-235.
3. Fawcett, E. E. (2004). The skeletal effects of a growth hormone-derived peptide (AOD9604) in the aged rat model of postmenopausal osteoporosis.
4. Shama, N., Kumari, R., Bais, S., & Shrivastava, A. (2019). Some important peptides and their role in obesity-current insights. Obesity Medicine, 16, 100144.
5. Thevis, M., & Schänzer, W. (2014). Analytical approaches for the detection of emerging therapeutics and non-approved drugs in human doping controls. Journal of pharmaceutical and biomedical analysis, 101, 66-83.
6. Heffernan, M., Summers, R. J., Thorburn, A., Ogru, E., Gianello, R., Jiang, W. J., & Ng, F. M. (2001). The Effects of Human GH and Its Lipolytic Fragment (AOD9604) on Lipid Metabolism Following Chronic Treatment in Obese Mice andβ 3-AR Knock-Out Mice. Endocrinology, 142(12), 5182-5189.
7. Halford, J. C. (2006). Obesity drugs in clinical development. Current Opinion in Investigational Drugs, 7(4), 312.